The patient died due to aggressive cancer transmitted from the donor.

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A 69-year-old patient living in the United States faced an unexpected situation after undergoing an organ transplant for liver cancer treatment. The patient, who contracted a more dangerous type of cancer from the transplanted organ, passed away within a few months.

This situation is known in the medical world as "transplant-related cancer," and it is so rare that it has not even made it into statistics. There are only a few similar cases in the medical literature.

Tragically, the outcome occurred six months after the initially successful transplant operation. Doctors believe that this rare disease originated from the organ donor. Investigations revealed that the lethal tumors were found only in the newly transplanted liver.

The patient had actually undergone the transplant due to liver cirrhosis caused by excessive alcohol consumption. During a routine check-up four months after the transplant at the Mayo Clinic in Phoenix, two masses were found in the liver. Initially, the seriousness of the situation was not understood. However, just six weeks later, three new masses appeared, and their number increased rapidly.

Detailed examinations revealed that these masses were metastases of aggressive lung cancer spreading to the liver. DNA tests confirmed that the cancer originated from the donor.

Interestingly, the 50-year-old organ donor had no history of cancer, and no issues were detected in pre-donation tests. It was later understood that the donor had undiagnosed advanced lung cancer before dying in 2019.

Due to the advanced stage of the cancer, the patient also lost the chance for a new liver transplant. Although chemotherapy initially offered hope, subsequent scans showed that the disease had become uncontrollable.

There is only one other case like this in medical history. In that case, lung cancer was discovered in the donor just a few days after a transplant was performed on a 41-year-old patient. However, this case became the first documented example of cancer originating from a donor without cancer.

According to a study conducted in 2013, the transmission of cancer through organ transplantation is so rare that it is impossible to even calculate the risk. Experts believe that there may be more such cases in reality, but most have not been recorded due to their rarity.