02.12.2025 18:52
Scientists are testing enteral ventilation, commonly known as "breathing through the backside," in humans to provide supplemental oxygen to patients with respiratory failure. While initial animal trials yielded positive results, safety tests conducted on humans have shown that the method is tolerable. Although its efficacy has not yet been confirmed, the technique holds promise for temporary support.
Scientists are exploring an extraordinary method to provide additional support for patients experiencing respiratory failure. This technique, commonly referred to as "breathing through the backside" and scientifically known as "enteral ventilation," is inspired by observations that some living beings can absorb oxygen through their intestines.
FIRST TESTS ON ANIMALS
Researchers, who set out with the idea of developing a new source of oxygen for patients whose lungs are not functioning adequately, conducted tests on mice and pigs. The animals were administered a special liquid with a high oxygen-carrying capacity rectally. The experiments showed that the liquid transferred oxygen from the intestinal wall into the bloodstream, resulting in a temporary increase in the animals' oxygen levels.
TESTS ON HUMANS SHOW PROMISE
The positive results obtained in animals led to the testing of the method in humans. In trials conducted in Japan in 2025, 27 healthy volunteers were administered the liquid in varying volumes. Most participants tolerated the liquid without issues, and no serious side effects were observed. Researchers noted that this is the first indication that the method may be safe.
OXYGEN EFFECT STILL UNDER INVESTIGATION
However, the method's actual capacity to provide oxygen in humans has not yet been proven. Scientists emphasize that new clinical studies with oxygen-rich liquids are needed to clarify this effect. Experts state that enteral ventilation will not replace existing respiratory therapies. For now, the technique is considered only as an additional or temporary support for patients experiencing respiratory failure.